The Human Systems Integration Conference 2021 (HSI2021), an INCOSE Conference, will be held virtually from 16 to 19 November, 2021. This first virtual edition of the HSI INCOSE Conference brings a fantastic environment to learn new things and to discuss your work with the worldwide Human Systems Integration community. Working together with the International Ergonomics Association (IEA) and Association for Computing Machinery (ACM) societies provides the opportunity for networking with members of other related professional societies, bringing a richness to the experience.